The T-SPOT®.COVID test: IN CLINIC BY A MEDICAL PROFESSIONAL (PREVIOUS INFECTION STATUS)

PRICE £195.00

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Buy the T-SPOT®.COVID test - In Clinic by a Medical Professional

  • CE Marked and carried out by professionals
  • Results within 2-3 working days
  • Highly accurate with a positive result agreement to previous positive PCR test result of >96.2% and negative result agreement in low risk individuals of 98.0%.

PRICE: £195

All new T cell test available now: First test to identify T Lymphocyte immune response to Covid-19.

We are the first private clinic to offer T Lymphocyte (T cell) testing to determine previously undetected lymphocyte immune responses to Covid-19 infection or vaccination. Hitherto, the only test available to assess an immune response was based on the presence of antibodies in identification of previous Covid-19 infections. However, the new T-SPOT®.COVID Test will enable individuals themselves to discover whether they have mounted a T cell immune response to Covid-19 as opposed to an antibody response which is the other way that the immune system deals with Covid-19 viral infection. The T-SPOT®.COVID Test looks for evidence of the immune response to covid-19. The aim is to answer the question: have I been exposed to Covid-19 and produced an immune response?

The T cell test is CE marked and registered for use in the UK.

See Dr Ali discuss the new test HERE.

Please note: The T cell test was developed for use and has been validated on venous blood samples (blood taken from a vein by a medical professional). Producing T cells takes time after initial contact with virus: testing should be undertaken 10 days or more following symptom onset.

 

T cell tests look for evidence of the immune response to Covid-19. The aim is to answer the question: have I been exposed to Covid-19 and produced an immune response? The T cell test is intended to detect a T cell-mediated immune response to SARS-CoV-2, which is different to serology which looks for an antibody response. T cells and antibodies are two arms of the adaptive immune response. The detection and measurement of each can provide different information about disease activity and an individual’s personal immunity. Antibodies may not be present in everyone who gets infected with SARS-CoV-2 and they may not be detectible after a long period of time. Evidence of a T cell response in the blood suggests previous exposure to the SARS-CoV-2 virus.

If current infection is suspected or you want to see if you are carrying covid-19 now, you need to use an antigen test (PCR test)

We do not yet know if the presence of SARS-CoV-2 specific T cells gives protection and makes you immune, nor how long any immunity will last. 

If a person is exposed to Covid-19, their immune system will react in order to start clearing the virus. Part of this response is to produce specific T cells which can either clear virus themselves (Killer T cells – or more correctly cytotoxic T cells), or support the work of other T cells and of antibodies (Helper T cells). Most patients produce T cells in response to infection or vaccination. The T cell test we use can detect both Killer and Helper T cells.

The T cell test (the T-SPOT.COVID test) is CE marked and registered for use in the UK by the MHRA. The test is highly accurate and was positive in 96.6 % of a group of previously infected individuals <60 days after infection and 83.3 % at >60 days after infection.

In a group of individuals without any history of disease, 98 % of samples tested were negative.

Producing T cells takes some time after initial contact with virus, but T cells may be detectable in the blood before antibodies are.

Venous blood sample

The T cell test was developed for use and has been validated on venous blood samples (blood taken from a vein by a medical professional). The test cannot be performed on samples of blood taken from a finger prick. This is why we only offer the test when a medical professional takes your sample from the vein, as recommended by the manufacturer. 

T cell test results

>8 spots Reactive
5-7 spots Borderline
<4 spots – Non-reactive

Results should be used in conjunction with information available from clinical evaluation and other diagnostic procedures.

Positive agreement to previous PCR positive result: 96.6% <60 days, 83.3% >60 days.
Negative agreement to a low risk population: 98.0%.

What does a ‘reactive’ T cell test result mean?

You have T cells that are reactive to the SARS-CoV-2 specific peptides used in the test. It is highly likely that they have been exposed to the SARS-CoV-2 virus.

What does a non-reactive T cell test result mean?

They do not have T cells that are reactive to the SARS-CoV-2 specific peptides used in the test. It is therefore unlikely that they have been exposed to the SARS-CoV-2 virus.

What does a borderline T cell test result mean?

Results near to the test cut off are always difficult to interpret. If they receive a borderline test result it is best to be re-tested to increase confidence in the test result.

  • In-clinic testing service in in Central London or Canary Wharf. If you require a same day appointment, and you are not able to book this online, please call 020 3916 5990 and we will see if we can fit you in;
  • Home visit from clinic nurse:  we may be able to provide a clinical testing service from the safety of your own home (only available for patients living in central London). Please call contact us for more information.

 

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