Our patients love Profhilo for its gentle refreshing, brightening and smoothing effects. Profhilo is currently one of the most popular skin-refreshing injectable treatments on the market for targeting all signs of aging. 

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What is Profhilo?

As we age, the fat, muscles, bone and skin in our faces gradually loses some natural volume, which can result in a sinking or sagging appearance, fine lines, wrinkles and folds. When we apply hyaluronic acid to our skin, the molecule in the solution is actually too large to pass further than the epidermis.

A unique hyaluronic acid injectable gel, Profhilo stimulates the production of collagen and elastin to counteract skin laxity and deliver a deep hydrating effect from under the skin.

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Face illustration showing where Profhilo can be injected

Key Areas for Treatment:

Profhilo enhances skin texture, hydration and overall radiance. It can also improve firmness and elasticity and promote refreshed and softer-looking skin. Profhilo is most commonly used for facial areas but can also be used to rejuvenate:

  • Neck
  • Décolletage
  • Arms
  • Knees
  • Backs of Hands

How Does Profhilo Work?

Hyaluronic acid is found naturally throughout the body, including in your skin. Profhilo is injected superficially in small micro injections across the face, neck or hands and improves overall skin quality and restores plumpness in the skin, which is lost in the aging process. Hyaluronic acid attracts and retains water, producing a volumising effect.

You will likely notice some improvement immediately after the first treatment but the full results are visible around 4 weeks after your second treatment. After around two months, your skin will also look more hydrated, radiant and youthful.

Expert Insight:

"Profhilo is one of our most popular treatments. It delivers a deep moisturisation effect that isn't achievable using skin creams alone and results in a smooth and healthy glow that our patients love. It's especially effective when used as part of a treatment programme with our technology services, such as the leading skin tightening treatment, Ultherapy."

Private Harley Street Clinic Profhilo Expert

Dr Emily Strong, Medical Aesthetic Practitioner

How much downtime is there for profhilo


Most people can resume normal activities in 24 hours, although you will likely notice some small bumps and localised redness at the injection sites for 24 - 48 hours after treatment. Very rarely, mild bruising can occur and may take a few days to appear.

how much does profhilo cost


Costs depend on the treatment recommended by your practitioner and the area that you're looking to treat but a single treatment will typically cost starting at £350. Full costs will be discussed with you before any treatment at your appointment.

How long is a profhilo appointment

Appointment Time

A full Profhilo treatment should only take around 30 minutes.

At your appointment, your practitioner may apply some skin numbing cream, and will mark out the target areas for injection, then administer your injections into specific sites for the most widespread and effective treatment.

How often do I need profhilo

Refresh Time

Profhilo lasts around 6 months when two treatments are given a month apart.

After you've had these initial treatments, we then recommend having a refresh appointment every 6 - 12 months, for optimum results.

Frequently Asked Questions

Profhilo Before and After Gallery:

Professional Insight...

Watch an example Profhilo treatment from the experts at IBSA, creators of Profhilo. In this video, you will see a professional injector administrating the treatment at the designated injection sites in the face. 

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"...looks so natural..."

"Karolina and her injectable fillers give a lift that looks so natural. The before and after photographs look remarkable but I still feel like I look like 'me'. She takes the time to explain every step and why she feels it would be best for me. I trust her fully as she has such a good eye! I've been seeing her for almost five years and look forward to every visit!"

"...never ceases to amaze me..."

"I have all my injectables done with Helen and am genuinely always so pleased with my results each time. Her ability to listen to my needs deliver natural results whilst maximising my features to look their best never ceases to amaze me. I have nothing but praise for Helen I tell all my friends about her!"

"...nothing but confidence ..."

"Karolina is professional, approachable and very easy to talk to. I go to her for my under-eye as well as cheek filler and each time her work has been amazing. She makes sure we talk thoroughly about what we are trying to achieve and keeping it looking natural. I have nothing but confidence in Karolina as I know the results will be outstanding."

"...honest and realistic.."

"I have been seeing Helen for almost a decade, and over this time have had various treatments from Ultherapy and various injectable fillers to combat the ravages of time. Helen has a great eye, is subtle in her approach to injectables and always stays up to date with new techniques and treatments. I trust her implicitly with my face - not only because she is skilful, but also because she is honest and realistic about options and results, and she has never let me down"

"...the results speak for themselves.."

"I've been seeing Helen for injectables for as long as I can remember. She really takes the time to get to know you and how your face is constructed.

She practices the utmost in hygiene and ensures any discomfort is minimal. The results speak for themselves.

I've had people comment on how well rested and radiant I look - never obvious, never overdone. I wouldn't go anywhere else!"


Private Harley Street Clinic uses genuine Profhilo
NAHYCO technology logo

Our Trusted Brands:

We only use brands that come personally recommended by our advanced nurse practitioners, who have years of professional experience with the wide variety of treatment options available and their various results.

Private Harley Street Clinic uses branded Profhilo treatment and our medical practitioners have received the official treatment training under the manufacturers trainers. 

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Ultherapy Goes Well With Profhilo


Profhilo treatment works especially well on the face and neck when used in combination with Ultherapy, an advanced Ultrasound Skin Tightening Treatment that lifts, rejuvenates and tightens skin.

Read More

How can we help? Get in Touch

If you'd like to enquire about booking a Profhilo appointment in our Marylebone Clinic, you can book a consultation online, or you can send us a message using the form below. One of our expert team will be in touch as soon as possible.

Alternatively, you can email us on

We look forward to hearing from you!


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